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Research/Lab Website
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PI Laboratory Functional Neurogenomics
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Biography
Amanda J Myers, PhD is the Principle Investigator of the Laboratory of Functional Neurogenomics at the University of Miami, Miller School of Medicine. She graduated from the University of Pennsylvania and performed work there mapping the connections of retina midget and bipolar cells as well as mapping dopaminergic pathways in the midbrains of Parkinson’s and Alzheimer’s disease subjects. Her PhD was obtained from Washington University in St Louis (“The Search for Novel Susceptibility Loci Involved in Late Onset Alzheimer's Disease: Significant Findings on Chromosome 10 and a Possible Protective Effect of the Urokinase Plasminogen Activator Gene”) in 2002 in the laboratory of Dr. Alison Goate. She received the ADRC director’s education award, a John Merlie fellowship and was a finalist for the O’Leary prize for outstanding research in neuroscience while at Washington University. She was funded via a resident research associateship through the National Academy of Sciences to perform her postdoctoral work at the National Institute on Aging in the laboratory of Dr. John A. Hardy. There she began her work mapping the relationship between DNA alleles and RNA profiles and how those relationships are changed in Alzheimer’s disease. She was nominated for a distinguished mentor award while at NIA. In 2007, she obtained a tenure-track post at the University of Miami, Miller School of Medicine where she has co-appointments in the Division of Neuroscience, the Department of Human Genetics and Genomics and the Center on Aging and is a founding member of the Academy of Medical Educators. She focuses on a collection of brain tissues obtained from over 3000 different individuals (~60% with pathologically confirmed Alzheimer’s Disease), with DNA, RNA and protein information on approximately 1/3 of those samples. Dr. Myers’ is currently funded by the National Institute on Aging, and has received funding from the National Institute of Mental Health, and the National Institute of Neurologic Disease and Stroke in the past. She reviews for multiple journals, NIH as well as multiple private foundations including the New Jersey Council on Autism, The French National Research Agency, the Qatar National Research Fund, the National Science Centre in Krakow Poland, the Netherlands Organization Veni programme and the Croatian Science Foundation. She is an Associate Editor for PLoS Genetics. She was elected as an Associate Member to the American College of Neuropsychopharmacology in December of 2012. Dr. Myers is currently interested in furthering the capture of omics targets in human brain tissues, novel analysis methods for capturing genomic control of expression as well as targeting best practice methods for following de novo hits from her screens. -
Education & Training
Education
Post Graduate Training
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Honors & Awards
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Teaching Interests
I teach or have taught undergraduates, graduates, medical students and residents. -
Research Interests
DNA, RNA and protein changes in Alzheimer's disease human brain tissue; iPSC modeling of Alzheimer's declines; Heat-shock proteins and trafficking in Alzheimer's disease -
Publications
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Professional Activities
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