Thomas K Harris

Assoc. Professor

Phone:
(305) 243-3358
Locator Code:
R629

 
Career

Education

2000Post Doctoral Johns Hopkins University School of Medicine
1994Ph.D. University of Mississippi Medical Center

Honors & Acknowledgements

Publications

2010

Horn, D., Zhou, W., Trevisson, E., Al-Ali, H., Harris, T. K., Salviati, L., Barrientos, A. (2010) The conserved mitochondrial twin Cx9C protein Cmc2 is a Cmc1 homolog essential for cytochrome c oxidase biogenesis. J. Biol. Chem. 285, 15088-15099.

Al-Ali, H., Rieger, M. E., Seldeen, K. L., Harris, T. K., Farooq, A., and Briegel, K. J. (2010) Biophysical characterization reveals structural disorder in the developmental transcriptional regulator LBH. Biochem. Biophys. Res. Comm. 391, 1104-1109.

2009

Harris, T. K., and Keshwani, M. M. (2009) Measurement of enzyme activity.Methods Enzymol. 463, 57-71.

Keshwani, M. M., Gao, X., and Harris, T. K. (2009) Mechanism of PDK1-catalyzed T229 phosphorylation of the S6K1 protein kinase. J. Biol. Chem. 284, 22611-22624.

2008

Keshwani, M. M., and Harris, T. K. (2008) Kinetic mechanism of fully activated S6K1 protein kinase. J. Biol. Chem. 283, 11972-11980.

Keshwani, M. M., Ross, D. B., Ragan, T. J., and Harris, T. K. (2008) Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain of the 70 kDa 40S ribosomal protein S6 kinase-1 aII isoform (S6K1aII). Protein Expr. Purif. 58, 32-41.

Ragan, T. J., Ross, D., Keshwani, M., and Harris, T. K. (2008) Expression, purification, and characterization of a structurally disordered but functional C-terminal autoinhibitory domain (AID) of the 70 kDa 40S ribosomal protein S6 kinase-1 (S6K1). Protein Expr. Purif. 57, 271-279.

2007

Yildiz, I., Gao, X., Harris, T. K., and Raymo, F. M. (2007) Fluoresence resonance energy transfer in quantum dot-protein kinase assemblies. J. Biomed. Biotech. 2007, 18081.

Al-Ali, H., Ragan, T. J., Gao, X., and Harris, T. K. (2007) Reconstitution of modular PDK1 functions on trans-splicing of the regulatory PH and catalytic kinase domains. Bioconjugate Chem. 18, 1294-1302.